Description:
This dataset contains the Motor evoked potential (MEP) signal of 84 healthy adult individuals who participated in three different TMS studies (N = 15, 33 & 36) at the Human Motor Control Section, NINDS, Bethesda, USA. 

Single monophasic TMS pulses were delivered using Magstim 200^2 (Magstim Ltd, Whitland, UK) connected to a 70mm figure-of-eight coil. The coil was positioned at an angle of about 45° from the midline and the handle pointing backwards so as to deliver a postero-anteriorly directed current in the brain. The motor hotspot of the target hand muscle was first identified while the hand was fully relaxed. Stimulus intensities ranged from 5% Maximum Stimulator Output (MSO) to 100% MSO and was provided in increments of 5% MSO. The order of the stimulation intensities was randomized and a total of 60 pulses with at least 3 pulses per intensity were delivered to the target motor hotspot.

MEP responses were recorded from abductor pollicis brevis (APB) (N = 34) or abductor digiti minimi ADM (N = 50) muscle groups  in response to TMS stimulation at their respective cortical hotspots. The EMG signal was amplified (gain = 1000) and filtered (20 - 2000Hz) by an EMG system (Nihon Kohden Neuropack, Japan). The signal was then digitized at 2000Hz using the CED micro 1401 laboratory interface (Cambridge Electronic Design Ltd, Cambridge, UK) and stored for offline analysis using their Signal version 7 software.